Cargando…
Mutational Profile of GNAQ (Q209) in Human Tumors
BACKGROUND: Frequent somatic mutations have recently been identified in the ras-like domain of the heterotrimeric G protein α-subunit (GNAQ) in blue naevi 83%, malignant blue naevi (50%) and ocular melanoma of the uvea (46%). The mutations exclusively affect codon 209 and result in GNAQ constitutive...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730032/ https://www.ncbi.nlm.nih.gov/pubmed/19718445 http://dx.doi.org/10.1371/journal.pone.0006833 |