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Biofilm on Ventriculo-Peritoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis

We describe a case of recurrent coccidioidal meningitis in which a fungal biofilm on the tip of ventriculo-peritoneal shunt tubing was likely responsible for a 4-year persistence of Coccidioides immitis, despite the patient’s taking an adequate dosage of fluconazole. Fungal biofilms should be consid...

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Detalles Bibliográficos
Autores principales: Davis, Larry E., Cook, Guy, Costerton, J. William
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730244/
https://www.ncbi.nlm.nih.gov/pubmed/11971770
http://dx.doi.org/10.3201/eid0804.010103
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author Davis, Larry E.
Cook, Guy
Costerton, J. William
author_facet Davis, Larry E.
Cook, Guy
Costerton, J. William
author_sort Davis, Larry E.
collection PubMed
description We describe a case of recurrent coccidioidal meningitis in which a fungal biofilm on the tip of ventriculo-peritoneal shunt tubing was likely responsible for a 4-year persistence of Coccidioides immitis, despite the patient’s taking an adequate dosage of fluconazole. Fungal biofilms should be considered as a cause for treatment failure and fungal persistence, especially when artificial prostheses or indwelling catheters are present.
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spelling pubmed-27302442009-09-16 Biofilm on Ventriculo-Peritoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis Davis, Larry E. Cook, Guy Costerton, J. William Emerg Infect Dis Research We describe a case of recurrent coccidioidal meningitis in which a fungal biofilm on the tip of ventriculo-peritoneal shunt tubing was likely responsible for a 4-year persistence of Coccidioides immitis, despite the patient’s taking an adequate dosage of fluconazole. Fungal biofilms should be considered as a cause for treatment failure and fungal persistence, especially when artificial prostheses or indwelling catheters are present. Centers for Disease Control and Prevention 2002-04 /pmc/articles/PMC2730244/ /pubmed/11971770 http://dx.doi.org/10.3201/eid0804.010103 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Davis, Larry E.
Cook, Guy
Costerton, J. William
Biofilm on Ventriculo-Peritoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis
title Biofilm on Ventriculo-Peritoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis
title_full Biofilm on Ventriculo-Peritoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis
title_fullStr Biofilm on Ventriculo-Peritoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis
title_full_unstemmed Biofilm on Ventriculo-Peritoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis
title_short Biofilm on Ventriculo-Peritoneal Shunt Tubing as a Cause of Treatment Failure in Coccidioidal Meningitis
title_sort biofilm on ventriculo-peritoneal shunt tubing as a cause of treatment failure in coccidioidal meningitis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730244/
https://www.ncbi.nlm.nih.gov/pubmed/11971770
http://dx.doi.org/10.3201/eid0804.010103
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