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Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

Induction of macrophage necrosis is an important strategy used by virulent Mycobacterium tuberculosis (Mtb) to avoid innate host defense. In contrast, attenuated Mtb causes apoptosis, which limits bacterial replication and promotes T cell cross priming by antigen presenting cells. Here we demonstrat...

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Detalles Bibliográficos
Autores principales: Divangahi, Maziar, Chen, Minjian, Gan, Huixian, Dejardins, Danielle, Hickman, Tyler T., Lee, David M., Fortune, Sarah, Behar, Samuel M., Remold, Heinz G.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730354/
https://www.ncbi.nlm.nih.gov/pubmed/19561612
http://dx.doi.org/10.1038/ni.1758

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