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Epigenetic Cross-Talk between DNA Methylation and Histone Modifications in Human Cancers
DNA methylation, histone modifications, and the chromatin structure are profoundly altered in human cancers. The silencing of cancer-related genes by these epigenetic regulators is recognized as a key mechanism in tumor formation. Recent findings revealed that DNA methylation and histone modificatio...
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| Formato: | Texto |
| Lenguaje: | English |
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Yonsei University College of Medicine
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730606/ https://www.ncbi.nlm.nih.gov/pubmed/19718392 http://dx.doi.org/10.3349/ymj.2009.50.4.455 |