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Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria
Mycolactones are a family of highly related macrocyclic polyketides that exhibit immunosuppressive and cytotoxic properties. First discovered in 1999, they are the primary virulence factors produced by the environmental human pathogen Mycobacterium ulcerans, the causative agent of Buruli ulcer, and...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730631/ https://www.ncbi.nlm.nih.gov/pubmed/18497894 http://dx.doi.org/10.1039/b803101k |