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Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria

Mycolactones are a family of highly related macrocyclic polyketides that exhibit immunosuppressive and cytotoxic properties. First discovered in 1999, they are the primary virulence factors produced by the environmental human pathogen Mycobacterium ulcerans, the causative agent of Buruli ulcer, and...

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Detalles Bibliográficos
Autores principales:	Hong, Hui, Demangel, Caroline, Pidot, Sacha J., Leadlay, Peter F., Stinear, Tim
Formato:	Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2008
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730631/ https://www.ncbi.nlm.nih.gov/pubmed/18497894 http://dx.doi.org/10.1039/b803101k

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