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dUTP incorporation into genomic DNA is linked to transcription in yeast
Highly-activated transcription is associated with eukaryotic genome instability, resulting in elevated rates of mitotic recombination and mutagenesis. The association between high transcription and genome stability is likely due to a variety of factors including an enhanced accumulation of DNA damag...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730915/ https://www.ncbi.nlm.nih.gov/pubmed/19448611 http://dx.doi.org/10.1038/nature08033 |