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Tnni3k Modifies Disease Progression in Murine Models of Cardiomyopathy

The Calsequestrin (Csq) transgenic mouse model of cardiomyopathy exhibits wide variation in phenotypic progression dependent on genetic background. Seven heart failure modifier (Hrtfm) loci modify disease progression and outcome. Here we report Tnni3k (cardiac Troponin I-interacting kinase) as the g...

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Detalles Bibliográficos
Autores principales:	Wheeler, Ferrin C., Tang, Hao, Marks, Odessa A., Hadnott, Tracy N., Chu, Pei-Lun, Mao, Lan, Rockman, Howard A., Marchuk, Douglas A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731170/ https://www.ncbi.nlm.nih.gov/pubmed/19763165 http://dx.doi.org/10.1371/journal.pgen.1000647

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