Whole Genome Amplification and De novo Assembly of Single Bacterial Cells

BACKGROUND: Single-cell genome sequencing has the potential to allow the in-depth exploration of the vast genetic diversity found in uncultured microbes. We used the marine cyanobacterium Prochlorococcus as a model system for addressing important challenges facing high-throughput whole genome amplif...

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Detalles Bibliográficos
Autores principales: Rodrigue, Sébastien, Malmstrom, Rex R., Berlin, Aaron M., Birren, Bruce W., Henn, Matthew R., Chisholm, Sallie W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731171/
https://www.ncbi.nlm.nih.gov/pubmed/19724646
http://dx.doi.org/10.1371/journal.pone.0006864

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