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CD8(+) T Cells Restrict Yersinia pseudotuberculosis Infection: Bypass of Anti-Phagocytosis by Targeting Antigen-Presenting Cells

All Yersinia species target and bind to phagocytic cells, but uptake and destruction of bacteria are prevented by injection of anti-phagocytic Yop proteins into the host cell. Here we provide evidence that CD8(+) T cells, which canonically eliminate intracellular pathogens, are important for restric...

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Detalles Bibliográficos
Autores principales: Bergman, Molly A., Loomis, Wendy P., Mecsas, Joan, Starnbach, Michael N., Isberg, Ralph R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731216/
https://www.ncbi.nlm.nih.gov/pubmed/19730693
http://dx.doi.org/10.1371/journal.ppat.1000573