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Leptin Contributes to the Adaptive Responses of Mice to High-Fat Diet Intake through Suppressing the Lipogenic Pathway

BACKGROUND: Leptin is an adipocyte-derived hormone that plays a critical role in energy homeostasis and lipid metabolism. Overnutrition-associated obesity is known to be accompanied by hyperleptinemia. However, the physiological actions of leptin in the metabolic responses to high-fat diet (HFD) int...

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Detalles Bibliográficos
Autores principales: Jiang, Lei, Wang, Qiong, Yu, Yue, Zhao, Feng, Huang, Ping, Zeng, Rong, Qi, Robert Z., Li, Wenjun, Liu, Yong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731220/
https://www.ncbi.nlm.nih.gov/pubmed/19727392
http://dx.doi.org/10.1371/journal.pone.0006884