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Leptin Contributes to the Adaptive Responses of Mice to High-Fat Diet Intake through Suppressing the Lipogenic Pathway
BACKGROUND: Leptin is an adipocyte-derived hormone that plays a critical role in energy homeostasis and lipid metabolism. Overnutrition-associated obesity is known to be accompanied by hyperleptinemia. However, the physiological actions of leptin in the metabolic responses to high-fat diet (HFD) int...
Autores principales: | Jiang, Lei, Wang, Qiong, Yu, Yue, Zhao, Feng, Huang, Ping, Zeng, Rong, Qi, Robert Z., Li, Wenjun, Liu, Yong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731220/ https://www.ncbi.nlm.nih.gov/pubmed/19727392 http://dx.doi.org/10.1371/journal.pone.0006884 |
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