The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation

OBJECTIVE: Significant new data suggest that metabolic disorders such as diabetes, obesity, and atherosclerosis all posses an important inflammatory component. Infiltrating macrophages contribute to both tissue-specific and systemic inflammation, which promotes insulin resistance. The complement cas...

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Detalles Bibliográficos
Autores principales: Mamane, Yaël, Chung Chan, Chi, Lavallee, Genevieve, Morin, Nicolas, Xu, Li-Jing, Huang, JingQi, Gordon, Robert, Thomas, Winston, Lamb, John, Schadt, Eric E., Kennedy, Brian P., Mancini, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731537/
https://www.ncbi.nlm.nih.gov/pubmed/19581423
http://dx.doi.org/10.2337/db09-0323

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