Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature

Valproic acid and its derivatives are commonly used to treat many psychiatric conditions in the elderly. Hyperammonemia is a less common but important side effect of these drugs. The elderly patient appears highly vulnerable to this side effect of this group of medications. In this paper, we systema...

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Detalles Bibliográficos
Autores principales: Mittal, Vikrant, Muralee, Sunanda, Tampi, Rajesh R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731545/
https://www.ncbi.nlm.nih.gov/pubmed/19724652
http://dx.doi.org/10.1155/2009/802121
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author Mittal, Vikrant
Muralee, Sunanda
Tampi, Rajesh R.
author_facet Mittal, Vikrant
Muralee, Sunanda
Tampi, Rajesh R.
author_sort Mittal, Vikrant
collection PubMed
description Valproic acid and its derivatives are commonly used to treat many psychiatric conditions in the elderly. Hyperammonemia is a less common but important side effect of these drugs. The elderly patient appears highly vulnerable to this side effect of this group of medications. In this paper, we systematically review the published literature for hyperammonemia induced by valproic acid and its derivatives. We describe the three reported cases and review possible treatment strategies for this condition.
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spelling pubmed-27315452009-09-01 Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature Mittal, Vikrant Muralee, Sunanda Tampi, Rajesh R. Case Rep Med Case Report Valproic acid and its derivatives are commonly used to treat many psychiatric conditions in the elderly. Hyperammonemia is a less common but important side effect of these drugs. The elderly patient appears highly vulnerable to this side effect of this group of medications. In this paper, we systematically review the published literature for hyperammonemia induced by valproic acid and its derivatives. We describe the three reported cases and review possible treatment strategies for this condition. Hindawi Publishing Corporation 2009 2009-08-19 /pmc/articles/PMC2731545/ /pubmed/19724652 http://dx.doi.org/10.1155/2009/802121 Text en Copyright © 2009 Vikrant Mittal et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mittal, Vikrant
Muralee, Sunanda
Tampi, Rajesh R.
Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature
title Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature
title_full Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature
title_fullStr Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature
title_full_unstemmed Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature
title_short Valproic Acid-Induced Hyperammonemia in the Elderly: A Review of the Literature
title_sort valproic acid-induced hyperammonemia in the elderly: a review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731545/
https://www.ncbi.nlm.nih.gov/pubmed/19724652
http://dx.doi.org/10.1155/2009/802121
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