The endogenous hydrogen sulfide producing enzyme cystathionine-β synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome

BACKGROUND: The pathogenesis of visceral hypersensitivity, a characteristic pathophysiological feature of irritable bowel syndrome (IBS), remains elusive. Recent studies suggest a role for hydrogen sulfide (H(2)S) in pain signaling but this has not been well studied in visceral models of hyperalgesi...

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Detalles Bibliográficos
Autores principales: Xu, Guang-Yin, Winston, John H, Shenoy, Mohan, Zhou, Shufang, Chen, Jiande DZ, Pasricha, Pankaj J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731739/
https://www.ncbi.nlm.nih.gov/pubmed/19660142
http://dx.doi.org/10.1186/1744-8069-5-44

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