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A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol
BACKGROUND: L-arabitol dehydrogenase (LAD) and xylitol dehydrogenase (XDH) are involved in the degradation of L-arabinose and D-xylose, which are among the most abundant monosaccharides on earth. Previous data demonstrated that LAD and XDH not only differ in the activity on their biological substrat...
Autores principales: | Rutten, Lucy, Ribot, Cecile, Trejo-Aguilar, Blanca, Wösten, Han AB, de Vries, Ronald P |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731777/ https://www.ncbi.nlm.nih.gov/pubmed/19674460 http://dx.doi.org/10.1186/1471-2180-9-166 |
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