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Elevated ethyl methanesulfonate (EMS) in nelfinavir mesylate (Viracept(®), Roche): overview
Roche's protease inhibitor nelfinavir mesylate (Viracept(®)) produced between March 2007-June 2007 was found to contain elevated levels of ethyl methanesulfonate (EMS), a known mutagen (alkylator) – leading to a global recall of the drug. EMS levels in a daily dose (2,500 mg Viracept/day) were...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731786/ https://www.ncbi.nlm.nih.gov/pubmed/19660105 http://dx.doi.org/10.1186/1742-6405-6-18 |