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Fidelity of SNP Array Genotyping Using Epstein Barr Virus-Transformed B-Lymphocyte Cell Lines: Implications for Genome-Wide Association Studies

BACKGROUND: As availability of primary cells can be limited for genetic studies of human disease, lymphoblastoid cell lines (LCL) are common sources of genomic DNA. LCL are created in a transformation process that entails in vitro infection of human B-lymphocytes with the Epstein-Barr Virus (EBV). M...

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Detalles Bibliográficos
Autores principales:	Herbeck, Joshua T., Gottlieb, Geoffrey S., Wong, Kim, Detels, Roger, Phair, John P., Rinaldo, Charles R., Jacobson, Lisa P., Margolick, Joseph B., Mullins, James I.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731852/ https://www.ncbi.nlm.nih.gov/pubmed/19730697 http://dx.doi.org/10.1371/journal.pone.0006915

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