Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees

We evaluated seropositivity to swine and human H1 influenza viruses in 74 swine farm owners, employees, their family members, and veterinarians in rural south-central Wisconsin, compared with 114 urban Milwaukee, Wisconsin, residents. The number of swine farm participants with positive serum hemaggl...

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Autores principales: Olsen, Christopher W., Brammer, Lynnette, Easterday, Bernard C., Arden, Nancy, Belay, Ermias, Baker, Inger, Cox, Nancy J.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732505/
https://www.ncbi.nlm.nih.gov/pubmed/12141967
http://dx.doi.org/10.3201/eid0808.010474
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author Olsen, Christopher W.
Brammer, Lynnette
Easterday, Bernard C.
Arden, Nancy
Belay, Ermias
Baker, Inger
Cox, Nancy J.
author_facet Olsen, Christopher W.
Brammer, Lynnette
Easterday, Bernard C.
Arden, Nancy
Belay, Ermias
Baker, Inger
Cox, Nancy J.
author_sort Olsen, Christopher W.
collection PubMed
description We evaluated seropositivity to swine and human H1 influenza viruses in 74 swine farm owners, employees, their family members, and veterinarians in rural south-central Wisconsin, compared with 114 urban Milwaukee, Wisconsin, residents. The number of swine farm participants with positive serum hemagglutination-inhibition (HI) antibody titers >40 to swine influenza viruses (17/74) was significantly higher (p<0.001) than the number of seropositive urban control samples (1/114). The geometric mean serum HI antibody titers to swine influenza viruses were also significantly higher (p<0.001) among the farm participants. Swine virus seropositivity was significantly (p<0.05) associated with being a farm owner or a farm family member, living on a farm, or entering the swine barn >4 days/week. Because pigs can play a role in generating genetically novel influenza viruses, swine farmers may represent an important sentinel population to evaluate the emergence of new pandemic influenza viruses.
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spelling pubmed-27325052009-09-16 Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees Olsen, Christopher W. Brammer, Lynnette Easterday, Bernard C. Arden, Nancy Belay, Ermias Baker, Inger Cox, Nancy J. Emerg Infect Dis Research We evaluated seropositivity to swine and human H1 influenza viruses in 74 swine farm owners, employees, their family members, and veterinarians in rural south-central Wisconsin, compared with 114 urban Milwaukee, Wisconsin, residents. The number of swine farm participants with positive serum hemagglutination-inhibition (HI) antibody titers >40 to swine influenza viruses (17/74) was significantly higher (p<0.001) than the number of seropositive urban control samples (1/114). The geometric mean serum HI antibody titers to swine influenza viruses were also significantly higher (p<0.001) among the farm participants. Swine virus seropositivity was significantly (p<0.05) associated with being a farm owner or a farm family member, living on a farm, or entering the swine barn >4 days/week. Because pigs can play a role in generating genetically novel influenza viruses, swine farmers may represent an important sentinel population to evaluate the emergence of new pandemic influenza viruses. Centers for Disease Control and Prevention 2002-08 /pmc/articles/PMC2732505/ /pubmed/12141967 http://dx.doi.org/10.3201/eid0808.010474 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Olsen, Christopher W.
Brammer, Lynnette
Easterday, Bernard C.
Arden, Nancy
Belay, Ermias
Baker, Inger
Cox, Nancy J.
Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees
title Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees
title_full Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees
title_fullStr Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees
title_full_unstemmed Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees
title_short Serologic Evidence of H1 Swine Influenza Virus Infection in Swine Farm Residents and Employees
title_sort serologic evidence of h1 swine influenza virus infection in swine farm residents and employees
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732505/
https://www.ncbi.nlm.nih.gov/pubmed/12141967
http://dx.doi.org/10.3201/eid0808.010474
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