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Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities

Methicillin-resistant Staphylococcus aureus (MRSA) has recently been reported to emerge in the community setting. We describe the investigation and control of a community-acquired outbreak of MRSA skin infections in a closed community of institutionalized adults with developmental disabilities. In a...

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Autores principales: Borer, Abraham, Gilad, Jacob, Yagupsky, Pablo, Peled, Nechama, Porat, Nurith, Trefler, Ronit, Shprecher-Levy, Hannah, Riesenberg, Klaris, Shipman, Miriam, Schlaeffer, Francisc
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732561/
https://www.ncbi.nlm.nih.gov/pubmed/12194775
http://dx.doi.org/10.3201/eid0809.020300
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author Borer, Abraham
Gilad, Jacob
Yagupsky, Pablo
Peled, Nechama
Porat, Nurith
Trefler, Ronit
Shprecher-Levy, Hannah
Riesenberg, Klaris
Shipman, Miriam
Schlaeffer, Francisc
author_facet Borer, Abraham
Gilad, Jacob
Yagupsky, Pablo
Peled, Nechama
Porat, Nurith
Trefler, Ronit
Shprecher-Levy, Hannah
Riesenberg, Klaris
Shipman, Miriam
Schlaeffer, Francisc
author_sort Borer, Abraham
collection PubMed
description Methicillin-resistant Staphylococcus aureus (MRSA) has recently been reported to emerge in the community setting. We describe the investigation and control of a community-acquired outbreak of MRSA skin infections in a closed community of institutionalized adults with developmental disabilities. In a 9-month period in 1997, 20 (71%) of 28 residents had 73 infectious episodes. Of the cultures, 60% and 32% obtained from residents and personnel, respectively, grew S. aureus; 96% and 27% were MRSA. All isolates were genetically related by pulsed-field gel electrophoresis and belonged to a phage type not previously described in the region. No known risk factors for MRSA acquisition were found. However, 58 antibiotic courses had been administered to 16 residents during the preceding 9 months. Infection control measures, antibiotic restriction, and appropriate therapy resulted in successful termination of this outbreak. Selective antibiotic pressure may result in the emergence, persistence, and dissemination of MRSA strains, causing prolonged disease.
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spelling pubmed-27325612009-09-16 Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities Borer, Abraham Gilad, Jacob Yagupsky, Pablo Peled, Nechama Porat, Nurith Trefler, Ronit Shprecher-Levy, Hannah Riesenberg, Klaris Shipman, Miriam Schlaeffer, Francisc Emerg Infect Dis Research Methicillin-resistant Staphylococcus aureus (MRSA) has recently been reported to emerge in the community setting. We describe the investigation and control of a community-acquired outbreak of MRSA skin infections in a closed community of institutionalized adults with developmental disabilities. In a 9-month period in 1997, 20 (71%) of 28 residents had 73 infectious episodes. Of the cultures, 60% and 32% obtained from residents and personnel, respectively, grew S. aureus; 96% and 27% were MRSA. All isolates were genetically related by pulsed-field gel electrophoresis and belonged to a phage type not previously described in the region. No known risk factors for MRSA acquisition were found. However, 58 antibiotic courses had been administered to 16 residents during the preceding 9 months. Infection control measures, antibiotic restriction, and appropriate therapy resulted in successful termination of this outbreak. Selective antibiotic pressure may result in the emergence, persistence, and dissemination of MRSA strains, causing prolonged disease. Centers for Disease Control and Prevention 2002-09 /pmc/articles/PMC2732561/ /pubmed/12194775 http://dx.doi.org/10.3201/eid0809.020300 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Borer, Abraham
Gilad, Jacob
Yagupsky, Pablo
Peled, Nechama
Porat, Nurith
Trefler, Ronit
Shprecher-Levy, Hannah
Riesenberg, Klaris
Shipman, Miriam
Schlaeffer, Francisc
Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities
title Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities
title_full Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities
title_fullStr Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities
title_full_unstemmed Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities
title_short Community-Acquired Methicillin-Resistant Staphylococcus aureus in Institutionalized Adults with Developmental Disabilities
title_sort community-acquired methicillin-resistant staphylococcus aureus in institutionalized adults with developmental disabilities
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732561/
https://www.ncbi.nlm.nih.gov/pubmed/12194775
http://dx.doi.org/10.3201/eid0809.020300
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