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Computing phenomenologic Adair-Klotz constants from microscopic MWC parameters
BACKGROUND: Modellers using the MWC allosteric framework have often found it difficult to validate their models. Indeed many experiments are not conducted with the notion of alternative conformations in mind and therefore do not (or cannot) measure relevant microscopic constant and parameters. Inste...
Autores principales: | Stefan, Melanie I, Edelstein, Stuart J, Le Novère, Nicolas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732593/ https://www.ncbi.nlm.nih.gov/pubmed/19602261 http://dx.doi.org/10.1186/1752-0509-3-68 |
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