Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea

The transcription machineries of Archaea and eukaryotes are similar in many aspects, but little is understood about archaeal chromatin and its role in transcription. Here, we describe the identification in hyperthermophilic Crenarchaeota and a Korarchaeon of an orthologue of the eukaryotic transcrip...

Descripción completa

Detalles Bibliográficos
Autores principales: Daniels, Jan-Peter, Kelly, Steven, Wickstead, Bill, Gull, Keith
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Discovery Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732611/
https://www.ncbi.nlm.nih.gov/pubmed/19640276
http://dx.doi.org/10.1186/1745-6150-4-24
_version_ 1782171059259179008
author Daniels, Jan-Peter
Kelly, Steven
Wickstead, Bill
Gull, Keith
author_facet Daniels, Jan-Peter
Kelly, Steven
Wickstead, Bill
Gull, Keith
author_sort Daniels, Jan-Peter
collection PubMed
description The transcription machineries of Archaea and eukaryotes are similar in many aspects, but little is understood about archaeal chromatin and its role in transcription. Here, we describe the identification in hyperthermophilic Crenarchaeota and a Korarchaeon of an orthologue of the eukaryotic transcription elongation factor Elf1, which has been shown to function in chromatin structure maintenance of actively transcribed templates. Our discovery has implications for the relationship of chromatin and transcription in Archaea and the evolution of these processes in eukaryotes. This article was reviewed by Chris P. Ponting and Eugene V. Koonin.
format Text
id pubmed-2732611
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-27326112009-08-27 Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea Daniels, Jan-Peter Kelly, Steven Wickstead, Bill Gull, Keith Biol Direct Discovery Notes The transcription machineries of Archaea and eukaryotes are similar in many aspects, but little is understood about archaeal chromatin and its role in transcription. Here, we describe the identification in hyperthermophilic Crenarchaeota and a Korarchaeon of an orthologue of the eukaryotic transcription elongation factor Elf1, which has been shown to function in chromatin structure maintenance of actively transcribed templates. Our discovery has implications for the relationship of chromatin and transcription in Archaea and the evolution of these processes in eukaryotes. This article was reviewed by Chris P. Ponting and Eugene V. Koonin. BioMed Central 2009-07-29 /pmc/articles/PMC2732611/ /pubmed/19640276 http://dx.doi.org/10.1186/1745-6150-4-24 Text en Copyright © 2009 Daniels et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Discovery Notes
Daniels, Jan-Peter
Kelly, Steven
Wickstead, Bill
Gull, Keith
Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea
title Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea
title_full Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea
title_fullStr Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea
title_full_unstemmed Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea
title_short Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea
title_sort identification of a crenarchaeal orthologue of elf1: implications for chromatin and transcription in archaea
topic Discovery Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732611/
https://www.ncbi.nlm.nih.gov/pubmed/19640276
http://dx.doi.org/10.1186/1745-6150-4-24
work_keys_str_mv AT danielsjanpeter identificationofacrenarchaealorthologueofelf1implicationsforchromatinandtranscriptioninarchaea
AT kellysteven identificationofacrenarchaealorthologueofelf1implicationsforchromatinandtranscriptioninarchaea
AT wicksteadbill identificationofacrenarchaealorthologueofelf1implicationsforchromatinandtranscriptioninarchaea
AT gullkeith identificationofacrenarchaealorthologueofelf1implicationsforchromatinandtranscriptioninarchaea

Ejemplares similares