A computational approach identifies two regions of Hepatitis C Virus E1 protein as interacting domains involved in viral fusion process

BACKGROUND: The E1 protein of Hepatitis C Virus (HCV) can be dissected into two distinct hydrophobic regions: a central domain containing an hypothetical fusion peptide (FP), and a C-terminal domain (CT) comprising two segments, a pre-anchor and a trans-membrane (TM) region. In the currently accepte...

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Detalles Bibliográficos
Autores principales: Bruni, Roberto, Costantino, Angela, Tritarelli, Elena, Marcantonio, Cinzia, Ciccozzi, Massimo, Rapicetta, Maria, El Sawaf, Gamal, Giuliani, Alessandro, Ciccaglione, Anna Rita
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732612/
https://www.ncbi.nlm.nih.gov/pubmed/19640267
http://dx.doi.org/10.1186/1472-6807-9-48

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732612/
https://www.ncbi.nlm.nih.gov/pubmed/19640267
http://dx.doi.org/10.1186/1472-6807-9-48

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