Improved Efficacy of a Gene Optimised Adenovirus-based Vaccine for Venezuelan Equine Encephalitis Virus

BACKGROUND: Optimisation of genes has been shown to be beneficial for expression of proteins in a range of applications. Optimisation has increased protein expression levels through improved codon usage of the genes and an increase in levels of messenger RNA. We have applied this to an adenovirus (a...

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Detalles Bibliográficos
Autores principales: Williams, Amanda J, O'Brien, Lyn M, Phillpotts, Robert J, Perkins, Stuart D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732613/
https://www.ncbi.nlm.nih.gov/pubmed/19646224
http://dx.doi.org/10.1186/1743-422X-6-118

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