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Towards optimal design of anti-malarial pharmacokinetic studies
BACKGROUND: Characterization of anti-malarial drug concentration profiles is necessary to optimize dosing, and thereby optimize cure rates and reduce both toxicity and the emergence of resistance. Population pharmacokinetic studies determine the drug concentration time profiles in the target patient...
Autores principales: | Simpson, Julie A, Jamsen, Kris M, Price, Ric N, White, Nicholas J, Lindegardh, Niklas, Tarning, Joel, Duffull, Stephen B |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732628/ https://www.ncbi.nlm.nih.gov/pubmed/19656413 http://dx.doi.org/10.1186/1475-2875-8-189 |
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