AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome

How XIST RNA strictly localizes across the inactive X chromosome is unknown; however, prophase release of human XIST RNA provides a clue. Tests of inhibitors that mimic mitotic chromatin modifications implicated an indirect role of PP1 (protein phosphatase 1), potentially via its interphase repressi...

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Detalles Bibliográficos
Autores principales: Hall, Lisa L., Byron, Meg, Pageau, Gayle, Lawrence, Jeanne B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733744/
https://www.ncbi.nlm.nih.gov/pubmed/19704020
http://dx.doi.org/10.1083/jcb.200811143

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