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Endocytosis of lipid-anchored proteins: excluding GEECs from the crowd
Endocytosis of glycosylphosphatidylinositol (GPI)-linked proteins via a specific pathway into GPI-enriched early endosomal compartments (GEECs) has been proposed. How sorting into this pathway may take place is unclear. In this issue, Bhagatji et al. (2009. J. Cell Biol. doi:10.1083/jcb.200903102) p...
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733753/ https://www.ncbi.nlm.nih.gov/pubmed/19687254 http://dx.doi.org/10.1083/jcb.200907119 |
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author | Nichols, Ben |
author_facet | Nichols, Ben |
author_sort | Nichols, Ben |
collection | PubMed |
description | Endocytosis of glycosylphosphatidylinositol (GPI)-linked proteins via a specific pathway into GPI-enriched early endosomal compartments (GEECs) has been proposed. How sorting into this pathway may take place is unclear. In this issue, Bhagatji et al. (2009. J. Cell Biol. doi:10.1083/jcb.200903102) provide an original mechanism for the sorting of lipid-anchored proteins that involves exclusion of bulky extracellular domains from clathrin-coated pits. |
format | Text |
id | pubmed-2733753 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-27337532010-02-24 Endocytosis of lipid-anchored proteins: excluding GEECs from the crowd Nichols, Ben J Cell Biol Reviews Endocytosis of glycosylphosphatidylinositol (GPI)-linked proteins via a specific pathway into GPI-enriched early endosomal compartments (GEECs) has been proposed. How sorting into this pathway may take place is unclear. In this issue, Bhagatji et al. (2009. J. Cell Biol. doi:10.1083/jcb.200903102) provide an original mechanism for the sorting of lipid-anchored proteins that involves exclusion of bulky extracellular domains from clathrin-coated pits. The Rockefeller University Press 2009-08-24 /pmc/articles/PMC2733753/ /pubmed/19687254 http://dx.doi.org/10.1083/jcb.200907119 Text en © 2009 Nichols This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/). |
spellingShingle | Reviews Nichols, Ben Endocytosis of lipid-anchored proteins: excluding GEECs from the crowd |
title | Endocytosis of lipid-anchored proteins: excluding GEECs from the crowd |
title_full | Endocytosis of lipid-anchored proteins: excluding GEECs from the crowd |
title_fullStr | Endocytosis of lipid-anchored proteins: excluding GEECs from the crowd |
title_full_unstemmed | Endocytosis of lipid-anchored proteins: excluding GEECs from the crowd |
title_short | Endocytosis of lipid-anchored proteins: excluding GEECs from the crowd |
title_sort | endocytosis of lipid-anchored proteins: excluding geecs from the crowd |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733753/ https://www.ncbi.nlm.nih.gov/pubmed/19687254 http://dx.doi.org/10.1083/jcb.200907119 |
work_keys_str_mv | AT nicholsben endocytosisoflipidanchoredproteinsexcludinggeecsfromthecrowd |