Slow progressive conduction and contraction defects in loss of Nkx2–5 mice after cardiomyocyte terminal differentiation

Mutations in homeoprotein NKX2–5 are linked to human congenital heart disease resulting in various cardiac anomalies, as well as postnatal progressive conduction defects and occasional left ventricular dysfunction, yet the function of Nkx2–5 in the postnatal period is largely unexplored. In the hear...

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Detalles Bibliográficos
Autores principales: Takeda, Morihiko, Briggs, Laura E., Wakimoto, Hiroko, Marks, Melissa H., Warren, Sonisha A., Lu, Jonathan T., Weinberg, Ellen O., Robertson, Keith D., Chien, Kenneth R., Kasahara, Hideko
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733927/
https://www.ncbi.nlm.nih.gov/pubmed/19546853
http://dx.doi.org/10.1038/labinvest.2009.59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733927/
https://www.ncbi.nlm.nih.gov/pubmed/19546853
http://dx.doi.org/10.1038/labinvest.2009.59

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