Synergy of Arbekacin-based Combinations Against Vancomycin Hetero-intermediate Staphylococcus aureus

This study was undertaken to evaluate the in vitro activities of arbekacin-based combination regimens against vancomycin hetero-intermediate Staphylococcus aureus (hetero-VISA). Combinations of arbekacin with vancomycin, rifampin, ampicillin-sulbactam, teicoplanin, or quinipristin-dalfopristin again...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Young, Oh, Won Sup, Ko, Kwan Soo, Heo, Sang Taek, Moon, Chi Sook, Ki, Hyun Kyun, Kiem, Sungmin, Peck, Kyong Ran, Song, Jae-Hoon
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2006
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733989/
https://www.ncbi.nlm.nih.gov/pubmed/16614499
http://dx.doi.org/10.3346/jkms.2006.21.2.188
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author Lee, Ji-Young
Oh, Won Sup
Ko, Kwan Soo
Heo, Sang Taek
Moon, Chi Sook
Ki, Hyun Kyun
Kiem, Sungmin
Peck, Kyong Ran
Song, Jae-Hoon
author_facet Lee, Ji-Young
Oh, Won Sup
Ko, Kwan Soo
Heo, Sang Taek
Moon, Chi Sook
Ki, Hyun Kyun
Kiem, Sungmin
Peck, Kyong Ran
Song, Jae-Hoon
author_sort Lee, Ji-Young
collection PubMed
description This study was undertaken to evaluate the in vitro activities of arbekacin-based combination regimens against vancomycin hetero-intermediate Staphylococcus aureus (hetero-VISA). Combinations of arbekacin with vancomycin, rifampin, ampicillin-sulbactam, teicoplanin, or quinipristin-dalfopristin against seven hetero-VISA strains and two methicillin-resistant S. aureus strains were evaluated by the time-kill assay. The combinations of arbekacin with vancomycin, teicoplanin, or ampicillin-sulbactam showed the synergistic interaction against hetero-VISA strains. Data suggest that these arbekacin-based combination regimens may be useful candidates for treatment options of hetero-VISA infections.
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spelling pubmed-27339892009-08-31 Synergy of Arbekacin-based Combinations Against Vancomycin Hetero-intermediate Staphylococcus aureus Lee, Ji-Young Oh, Won Sup Ko, Kwan Soo Heo, Sang Taek Moon, Chi Sook Ki, Hyun Kyun Kiem, Sungmin Peck, Kyong Ran Song, Jae-Hoon J Korean Med Sci Original Article This study was undertaken to evaluate the in vitro activities of arbekacin-based combination regimens against vancomycin hetero-intermediate Staphylococcus aureus (hetero-VISA). Combinations of arbekacin with vancomycin, rifampin, ampicillin-sulbactam, teicoplanin, or quinipristin-dalfopristin against seven hetero-VISA strains and two methicillin-resistant S. aureus strains were evaluated by the time-kill assay. The combinations of arbekacin with vancomycin, teicoplanin, or ampicillin-sulbactam showed the synergistic interaction against hetero-VISA strains. Data suggest that these arbekacin-based combination regimens may be useful candidates for treatment options of hetero-VISA infections. The Korean Academy of Medical Sciences 2006-04 2006-04-20 /pmc/articles/PMC2733989/ /pubmed/16614499 http://dx.doi.org/10.3346/jkms.2006.21.2.188 Text en Copyright © 2006 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lee, Ji-Young
Oh, Won Sup
Ko, Kwan Soo
Heo, Sang Taek
Moon, Chi Sook
Ki, Hyun Kyun
Kiem, Sungmin
Peck, Kyong Ran
Song, Jae-Hoon
Synergy of Arbekacin-based Combinations Against Vancomycin Hetero-intermediate Staphylococcus aureus
title Synergy of Arbekacin-based Combinations Against Vancomycin Hetero-intermediate Staphylococcus aureus
title_full Synergy of Arbekacin-based Combinations Against Vancomycin Hetero-intermediate Staphylococcus aureus
title_fullStr Synergy of Arbekacin-based Combinations Against Vancomycin Hetero-intermediate Staphylococcus aureus
title_full_unstemmed Synergy of Arbekacin-based Combinations Against Vancomycin Hetero-intermediate Staphylococcus aureus
title_short Synergy of Arbekacin-based Combinations Against Vancomycin Hetero-intermediate Staphylococcus aureus
title_sort synergy of arbekacin-based combinations against vancomycin hetero-intermediate staphylococcus aureus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733989/
https://www.ncbi.nlm.nih.gov/pubmed/16614499
http://dx.doi.org/10.3346/jkms.2006.21.2.188
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