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Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection
We reviewed our experience with resection of recurrent lung cancer to evaluate the benefit and risk of the procedure. From December 1994 to December 2003, 29 consecutive patients underwent pulmonary resections for recurrent lung cancer. The mean duration from the first resection to second surgery wa...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Academy of Medical Sciences
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733995/ https://www.ncbi.nlm.nih.gov/pubmed/16614505 http://dx.doi.org/10.3346/jkms.2006.21.2.224 |
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author | Kim, Hyoung Soo I, Hoseok Choi, Yong Soo Kim, Kwhanmien Shim, Young Mog Kim, Jhingook |
author_facet | Kim, Hyoung Soo I, Hoseok Choi, Yong Soo Kim, Kwhanmien Shim, Young Mog Kim, Jhingook |
author_sort | Kim, Hyoung Soo |
collection | PubMed |
description | We reviewed our experience with resection of recurrent lung cancer to evaluate the benefit and risk of the procedure. From December 1994 to December 2003, 29 consecutive patients underwent pulmonary resections for recurrent lung cancer. The mean duration from the first resection to second surgery was 25.4±15.1 months for the definite 2nd primary lung cancer (n=20) and 8.9±5.7 months for metastatic lung cancer (n=9). The procedures at the second operations were completion-pneumonectomy in 11 patients, lobectomy in 5 patients, wedge resection in 12 patients and resection and anastomosis of trachea in 1 patient. Morbidity was observed in 6 (21%) of the patients and the in-hospital mortality was two patients (7%) after the repeated lung resection. Tumor recurrence after reoperation was observed in 14 patients (48%). The actuarial 5-yr survival rate was 69% and the 5-yr disease free rate following reoperation was 44%. No significant difference was found in overall survival and disease free survival between the 2nd primary lung cancer group and the metastatic lung cancer group. The recurrence rate following reoperation was significantly different between the wedge resection group and lobectomy/completion pneumonectomy group (p=0.008), but the survival rate was not significantly different (p=0.41). Surgical intervention for recurrent lung cancers can be performed with acceptable mortality and morbidity. If tolerable, completion pneumonectomy or lobectomy is recommended for resection of recurrent lung cancer. |
format | Text |
id | pubmed-2733995 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-27339952009-08-31 Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection Kim, Hyoung Soo I, Hoseok Choi, Yong Soo Kim, Kwhanmien Shim, Young Mog Kim, Jhingook J Korean Med Sci Original Article We reviewed our experience with resection of recurrent lung cancer to evaluate the benefit and risk of the procedure. From December 1994 to December 2003, 29 consecutive patients underwent pulmonary resections for recurrent lung cancer. The mean duration from the first resection to second surgery was 25.4±15.1 months for the definite 2nd primary lung cancer (n=20) and 8.9±5.7 months for metastatic lung cancer (n=9). The procedures at the second operations were completion-pneumonectomy in 11 patients, lobectomy in 5 patients, wedge resection in 12 patients and resection and anastomosis of trachea in 1 patient. Morbidity was observed in 6 (21%) of the patients and the in-hospital mortality was two patients (7%) after the repeated lung resection. Tumor recurrence after reoperation was observed in 14 patients (48%). The actuarial 5-yr survival rate was 69% and the 5-yr disease free rate following reoperation was 44%. No significant difference was found in overall survival and disease free survival between the 2nd primary lung cancer group and the metastatic lung cancer group. The recurrence rate following reoperation was significantly different between the wedge resection group and lobectomy/completion pneumonectomy group (p=0.008), but the survival rate was not significantly different (p=0.41). Surgical intervention for recurrent lung cancers can be performed with acceptable mortality and morbidity. If tolerable, completion pneumonectomy or lobectomy is recommended for resection of recurrent lung cancer. The Korean Academy of Medical Sciences 2006-04 2006-04-20 /pmc/articles/PMC2733995/ /pubmed/16614505 http://dx.doi.org/10.3346/jkms.2006.21.2.224 Text en Copyright © 2006 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Hyoung Soo I, Hoseok Choi, Yong Soo Kim, Kwhanmien Shim, Young Mog Kim, Jhingook Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection |
title | Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection |
title_full | Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection |
title_fullStr | Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection |
title_full_unstemmed | Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection |
title_short | Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection |
title_sort | surgical resection of recurrent lung cancer in patients following curative resection |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2733995/ https://www.ncbi.nlm.nih.gov/pubmed/16614505 http://dx.doi.org/10.3346/jkms.2006.21.2.224 |
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