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The Immune System Strikes Back: Cellular Immune Responses against Indoleamine 2,3-dioxygenase

BACKGROUND: The enzyme indoleamine 2,3-dioxygenase (IDO) exerts an well established immunosuppressive function in cancer. IDO is expressed within the tumor itself as well as in antigen-presenting cells in tumor-draining lymph nodes, where it promotes the establishment of peripheral immune tolerance...

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Detalles Bibliográficos
Autores principales: Sørensen, Rikke Bæk, Berge-Hansen, Linda, Junker, Niels, Hansen, Christina Aaen, Hadrup, Sine Reker, Schumacher, Ton N. M., Svane, Inge Marie, Becker, Jürgen C., Straten, Per thor, Andersen, Mads Hald
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734165/
https://www.ncbi.nlm.nih.gov/pubmed/19738905
http://dx.doi.org/10.1371/journal.pone.0006910