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The Immune System Strikes Back: Cellular Immune Responses against Indoleamine 2,3-dioxygenase
BACKGROUND: The enzyme indoleamine 2,3-dioxygenase (IDO) exerts an well established immunosuppressive function in cancer. IDO is expressed within the tumor itself as well as in antigen-presenting cells in tumor-draining lymph nodes, where it promotes the establishment of peripheral immune tolerance...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734165/ https://www.ncbi.nlm.nih.gov/pubmed/19738905 http://dx.doi.org/10.1371/journal.pone.0006910 |