The Cellular Phenotype of Roberts Syndrome Fibroblasts as Revealed by Ectopic Expression of ESCO2

Cohesion between sister chromatids is essential for faithful chromosome segregation. In budding yeast, the acetyltransferase Eco1/Ctf7 establishes cohesion during DNA replication in S phase and in response to DNA double strand breaks in G2/M phase. In humans two Eco1 orthologs exist: ESCO1 and ESCO2...

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Detalles Bibliográficos
Autores principales: van der Lelij, Petra, Godthelp, Barbara C., van Zon, Wouter, van Gosliga, Djoke, Oostra, Anneke B., Steltenpool, Jûrgen, de Groot, Jan, Scheper, Rik J., Wolthuis, Rob M., Waisfisz, Quinten, Darroudi, Firouz, Joenje, Hans, de Winter, Johan P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734174/
https://www.ncbi.nlm.nih.gov/pubmed/19738907
http://dx.doi.org/10.1371/journal.pone.0006936

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