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RAD50 Is Required for Efficient Initiation of Resection and Recombinational Repair at Random, γ-Induced Double-Strand Break Ends

Resection of DNA double-strand break (DSB) ends is generally considered a critical determinant in pathways of DSB repair and genome stability. Unlike for enzymatically induced site-specific DSBs, little is known about processing of random “dirty-ended” DSBs created by DNA damaging agents such as ion...

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Detalles Bibliográficos
Autores principales:	Westmoreland, Jim, Ma, Wenjian, Yan, Yan, Van Hulle, Kelly, Malkova, Anna, Resnick, Michael A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734177/ https://www.ncbi.nlm.nih.gov/pubmed/19763170 http://dx.doi.org/10.1371/journal.pgen.1000656

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