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l-arginine supplementation reduces cardiac noradrenergic neurotransmission in spontaneously hypertensive rats
Spontaneously hypertensive rats (SHR) are known to have cardiac noradrenergic hyperactivity due to an impaired nitric oxide (NO)–cGMP pathway. We hypothesized that dietary l-arginine supplementation may correct this autonomic phenotype. Male SHR and Wistar Kyoto rats (WKY) aged 16–18 weeks were give...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Academic Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734311/ https://www.ncbi.nlm.nih.gov/pubmed/19362092 http://dx.doi.org/10.1016/j.yjmcc.2009.03.023 |