Cargando…
Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7
Paraplegin is an m-AAA protease of the mitochondrial inner membrane that is linked to hereditary spastic paraplegias. The gene encodes an FtsH-homology protease domain in tandem with an AAA+ homology ATPase domain. The protein is believed to form a hexamer that uses ATPase-driven conformational chan...
Autores principales: | Karlberg, Tobias, van den Berg, Susanne, Hammarström, Martin, Sagemark, Johanna, Johansson, Ida, Holmberg-Schiavone, Lovisa, Schüler, Herwig |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734466/ https://www.ncbi.nlm.nih.gov/pubmed/19841671 http://dx.doi.org/10.1371/journal.pone.0006975 |
Ejemplares similares
-
Biochemical Discrimination between Selenium and Sulfur 1: A Single Residue Provides Selenium Specificity to Human Selenocysteine Lyase
por: Collins, Ruairi, et al.
Publicado: (2012) -
Loss of the Drosophilam-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration
por: Pareek, Gautam, et al.
Publicado: (2018) -
Alternative Splicing of Spg7, a Gene Involved in Hereditary Spastic Paraplegia, Encodes a Variant of Paraplegin Targeted to the Endoplasmic Reticulum
por: Mancuso, Giuseppe, et al.
Publicado: (2012) -
Comparative Structural Analysis of Human DEAD-Box RNA Helicases
por: Schütz, Patrick, et al.
Publicado: (2010) -
Crystal Structures of the ATPase Domains of Four Human Hsp70 Isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78
por: Wisniewska, Magdalena, et al.
Publicado: (2010)