Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype

BACKGROUND: The Warburg phenotype in cancer cells has been long recognized, but there is still limited insight in the consecutive metabolic alterations that characterize its establishment. We obtained better understanding of the coupling between metabolism and malignant transformation by studying mo...

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Detalles Bibliográficos
Autores principales: de Groof, Ad JC, te Lindert, Mariska M, van Dommelen, Michiel MT, Wu, Min, Willemse, Marieke, Smift, Amy L, Winer, Mike, Oerlemans, Frank, Pluk, Helma, Fransen, Jack AM, Wieringa, Bé
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734543/
https://www.ncbi.nlm.nih.gov/pubmed/19646236
http://dx.doi.org/10.1186/1476-4598-8-54

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