Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors

BACKGROUND: P2X3 and P2X2/3 purinergic receptor-channels, expressed in primary sensory neurons that mediate nociception, have been implicated in neuropathic and inflammatory pain responses. The phospholipids phosphatidylinositol 4,5-bisphosphate (PIP(2)) and phosphatidylinositol 3,4,5-trisphosphate...

Descripción completa

Detalles Bibliográficos
Autores principales: Mo, Gary, Bernier, Louis-Philippe, Zhao, Qi, Chabot-Doré, Anne-Julie, Ase, Ariel R, Logothetis, Diomedes, Cao, Chang-Qing, Séguéla, Philippe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734547/
https://www.ncbi.nlm.nih.gov/pubmed/19671169
http://dx.doi.org/10.1186/1744-8069-5-47

Ejemplares similares

Ejemplares similares