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Functional mapping of the fission yeast DNA polymerase δ B-subunit Cdc1 by site-directed and random pentapeptide insertion mutagenesis

BACKGROUND: DNA polymerase δ plays an essential role in chromosomal DNA replication in eukaryotic cells, being responsible for synthesising the bulk of the lagging strand. In fission yeast, Pol δ is a heterotetrameric enzyme comprising four evolutionarily well-conserved proteins: the catalytic subun...

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Detalles Bibliográficos
Autores principales:	Sanchez Garcia, Javier, Baranovskiy, Andrey G, Knatko, Elena V, Gray, Fiona C, Tahirov, Tahir H, MacNeill, Stuart A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734569/ https://www.ncbi.nlm.nih.gov/pubmed/19686603 http://dx.doi.org/10.1186/1471-2199-10-82

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