Genetic Variation in the Proximal Promoter of ABC and SLC Superfamilies: Liver and Kidney Specific Expression and Promoter Activity Predict Variation

Membrane transporters play crucial roles in the cellular uptake and efflux of an array of small molecules including nutrients, environmental toxins, and many clinically used drugs. We hypothesized that common genetic variation in the proximal promoter regions of transporter genes contribute to obser...

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Detalles Bibliográficos
Autores principales: Hesselson, Stephanie E., Matsson, Pär, Shima, James E., Fukushima, Hisayo, Yee, Sook Wah, Kobayashi, Yuya, Gow, Jason M., Ha, Connie, Ma, Benjamin, Poon, Annie, Johns, Susan J., Stryke, Doug, Castro, Richard A., Tahara, Harunobu, Choi, Ji Ha, Chen, Ligong, Picard, Nicolas, Sjödin, Elin, Roelofs, Maarke J. E., Ferrin, Thomas E., Myers, Richard, Kroetz, Deanna L., Kwok, Pui-Yan, Giacomini, Kathleen M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735003/
https://www.ncbi.nlm.nih.gov/pubmed/19742321
http://dx.doi.org/10.1371/journal.pone.0006942

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