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Dimerization of Tetherin Is Not Essential for Its Antiviral Activity against Lassa and Marburg Viruses
Tetherin (also known as BST2, CD317 or HM1.24) has recently been reported to inhibit a wide range of viruses. However, the antiviral mechanism of action of tetherin has not been determined. Both ends of the tetherin molecule are associated with the plasma membrane and it forms a homodimer. Therefore...
Autores principales: | Sakuma, Toshie, Sakurai, Akira, Yasuda, Jiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735005/ https://www.ncbi.nlm.nih.gov/pubmed/19742323 http://dx.doi.org/10.1371/journal.pone.0006934 |
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