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Repression of RNA Polymerase II Elongation In Vivo Is Critically Dependent on the C-Terminus of Spt5
The stalling of RNA polymerase II (RNAPII) at the promoters of many genes, including developmental regulators, stress-responsive genes, and HIVLTR, suggests transcription elongation as a critical regulatory step in addition to initiation. Spt5, the large subunit of the DRB sensitivity-inducing facto...
Autores principales: | Chen, Hui, Contreras, Xavier, Yamaguchi, Yuki, Handa, Hiroshi, Peterlin, B. Matija, Guo, Su |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735033/ https://www.ncbi.nlm.nih.gov/pubmed/19742326 http://dx.doi.org/10.1371/journal.pone.0006918 |
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