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Complete but curtailed T cell response to very low affinity antigen
Following an infection, CD8(+) T cells are activated and undergo a characteristic kinetic sequence of rapid expansion, subsequent contraction and formation of memory cells1–3. The pool of naïve T cell clones is diverse and contains cells bearing T cell antigen receptors (TCR) that differ in their af...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735344/ https://www.ncbi.nlm.nih.gov/pubmed/19182777 http://dx.doi.org/10.1038/nature07657 |