SNP-o-matic

Motivation: High throughput sequencing technologies generate large amounts of short reads. Mapping these to a reference sequence consumes large amounts of processing time and memory, and read mapping errors can lead to noisy or incorrect alignments. SNP-o-matic is a fast, memory-efficient and string...

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Detalles Bibliográficos
Autores principales: Manske, Heinrich Magnus, Kwiatkowski, Dominic P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735664/
https://www.ncbi.nlm.nih.gov/pubmed/19574284
http://dx.doi.org/10.1093/bioinformatics/btp403
Descripción
Sumario:Motivation: High throughput sequencing technologies generate large amounts of short reads. Mapping these to a reference sequence consumes large amounts of processing time and memory, and read mapping errors can lead to noisy or incorrect alignments. SNP-o-matic is a fast, memory-efficient and stringent read mapping tool offering a variety of analytical output functions, with an emphasis on genotyping. Availability: http://snpomatic.sourceforge.net Contact: mm6@sanger.ac.uk Supplementary information: Supplementary data are available at Bioinformatics online.

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