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Modeling and Analysis of the Molecular Basis of Pain in Sensory Neurons

Intracellular calcium dynamics are critical to cellular functions like pain transmission. Extracellular ATP plays an important role in modulating intracellular calcium levels by interacting with the P2 family of surface receptors. In this study, we developed a mechanistic mathematical model of ATP-i...

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Detalles Bibliográficos
Autores principales: Song, Sang Ok, Varner, Jeffrey
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735677/
https://www.ncbi.nlm.nih.gov/pubmed/19750220
http://dx.doi.org/10.1371/journal.pone.0006758