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Brachytherapy for Prostate Cancer: A Systematic Review

Low-dose rate brachytherapy has become a mainstream treatment option for men diagnosed with prostate cancer because of excellent long-term treatment outcomes in low-, intermediate-, and high-risk patients. To a great extend due to patient lead advocacy for minimally invasive treatment options, high-...

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Autores principales: Koukourakis, Georgios, Kelekis, Nikolaos, Armonis, Vassilios, Kouloulias, Vassilios
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735748/
https://www.ncbi.nlm.nih.gov/pubmed/19730753
http://dx.doi.org/10.1155/2009/327945
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author Koukourakis, Georgios
Kelekis, Nikolaos
Armonis, Vassilios
Kouloulias, Vassilios
author_facet Koukourakis, Georgios
Kelekis, Nikolaos
Armonis, Vassilios
Kouloulias, Vassilios
author_sort Koukourakis, Georgios
collection PubMed
description Low-dose rate brachytherapy has become a mainstream treatment option for men diagnosed with prostate cancer because of excellent long-term treatment outcomes in low-, intermediate-, and high-risk patients. To a great extend due to patient lead advocacy for minimally invasive treatment options, high-quality prostate implants have become widely available in the US, Europe, and Japan. High-dose-rate (HDR) afterloading brachytherapy in the management of localised prostate cancer has practical, physical, and biological advantages over low-dose-rate seed brachytherapy. There are no free live sources used, no risk of source loss, and since the implant is a temporary procedure following discharge no issues with regard to radioprotection use of existing facilities exist. Patients with localized prostate cancer may benefit from high-dose-rate brachytherapy, which may be used alone in certain circumstances or in combination with external-beam radiotherapy in other settings. The purpose of this paper is to present the essentials of brachytherapies techniques along with the most important studies that support their effectiveness in the treatment of prostate cancer.
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spelling pubmed-27357482009-09-03 Brachytherapy for Prostate Cancer: A Systematic Review Koukourakis, Georgios Kelekis, Nikolaos Armonis, Vassilios Kouloulias, Vassilios Adv Urol Review Article Low-dose rate brachytherapy has become a mainstream treatment option for men diagnosed with prostate cancer because of excellent long-term treatment outcomes in low-, intermediate-, and high-risk patients. To a great extend due to patient lead advocacy for minimally invasive treatment options, high-quality prostate implants have become widely available in the US, Europe, and Japan. High-dose-rate (HDR) afterloading brachytherapy in the management of localised prostate cancer has practical, physical, and biological advantages over low-dose-rate seed brachytherapy. There are no free live sources used, no risk of source loss, and since the implant is a temporary procedure following discharge no issues with regard to radioprotection use of existing facilities exist. Patients with localized prostate cancer may benefit from high-dose-rate brachytherapy, which may be used alone in certain circumstances or in combination with external-beam radiotherapy in other settings. The purpose of this paper is to present the essentials of brachytherapies techniques along with the most important studies that support their effectiveness in the treatment of prostate cancer. Hindawi Publishing Corporation 2009 2009-09-01 /pmc/articles/PMC2735748/ /pubmed/19730753 http://dx.doi.org/10.1155/2009/327945 Text en Copyright © 2009 Georgios Koukourakis et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Koukourakis, Georgios
Kelekis, Nikolaos
Armonis, Vassilios
Kouloulias, Vassilios
Brachytherapy for Prostate Cancer: A Systematic Review
title Brachytherapy for Prostate Cancer: A Systematic Review
title_full Brachytherapy for Prostate Cancer: A Systematic Review
title_fullStr Brachytherapy for Prostate Cancer: A Systematic Review
title_full_unstemmed Brachytherapy for Prostate Cancer: A Systematic Review
title_short Brachytherapy for Prostate Cancer: A Systematic Review
title_sort brachytherapy for prostate cancer: a systematic review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735748/
https://www.ncbi.nlm.nih.gov/pubmed/19730753
http://dx.doi.org/10.1155/2009/327945
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