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Shiga Toxin and Lipopolysaccharide Induce Platelet-Leukocyte Aggregates and Tissue Factor Release, a Thrombotic Mechanism in Hemolytic Uremic Syndrome

BACKGROUND: Aggregates formed between leukocytes and platelets in the circulation lead to release of tissue factor (TF)–bearing microparticles contributing to a prothrombotic state. As enterohemorrhagic Escherichia coli (EHEC) may cause hemolytic uremic syndrome (HUS), in which microthrombi cause ti...

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Detalles Bibliográficos
Autores principales:	Ståhl, Anne-lie, Sartz, Lisa, Nelsson, Anders, Békássy, Zivile D., Karpman, Diana
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735777/ https://www.ncbi.nlm.nih.gov/pubmed/19750223 http://dx.doi.org/10.1371/journal.pone.0006990

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