Modulation of intracellular ROS levels by TIGAR controls autophagy

The p53-inducible TIGAR protein functions as a fructose-2,6-bisphosphatase, promoting the pentose phosphate pathway and helping to lower intracellular reactive oxygen species (ROS). ROS functions in the regulation of many cellular responses, including autophagy—a response to stress conditions such a...

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Detalles Bibliográficos
Autores principales: Bensaad, Karim, Cheung, Eric C, Vousden, Karen H
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736014/
https://www.ncbi.nlm.nih.gov/pubmed/19713938
http://dx.doi.org/10.1038/emboj.2009.242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736014/
https://www.ncbi.nlm.nih.gov/pubmed/19713938
http://dx.doi.org/10.1038/emboj.2009.242

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