Mechanisms of toxic smoke inhalation and burn injury: Role of neutral endopeptidase and vascular leakage in mice

The effects of neutral endopeptidase (NEP) in acute inflammation in the lung were studied using a newly developed murine model of smoke and burn (SB) injury. C57BL/6 mice were pretreated with an i.v. dose of a specific NEP antagonist CGS-24592 (10 mg/Kg) 1 h prior to SB injury (n = 5–8/group). Mice...

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Detalles Bibliográficos
Autores principales: Jacob, Sam, Deyo, Donald J., Cox, Robert A., Traber, Daniel L., Herndon, David N., Hawkins, Hal K.
Formato: Texto
Lenguaje:English
Publicado: Informa Healthcare 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736052/
https://www.ncbi.nlm.nih.gov/pubmed/19727335
http://dx.doi.org/10.1080/15376510902725649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736052/
https://www.ncbi.nlm.nih.gov/pubmed/19727335
http://dx.doi.org/10.1080/15376510902725649

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