RNA interference for apoptosis signal-regulating kinase-1 (ASK-1) rescues photoreceptor death in the rd1 mouse

PURPOSE: To evaluate whether RNA interference against apoptosis signal-regulating kinase-1 (ASK-1), a gene involved in stress-induced apoptosis, inhibits photoreceptor death in retinal degeneration 1 (rd1) mice. METHODS: Retinal explants from rd1 mice were subjected to organ cultures on postnatal da...

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Detalles Bibliográficos
Autores principales: Sekimukai, Daisuke, Honda, Shigeru, Negi, Akira
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736151/
https://www.ncbi.nlm.nih.gov/pubmed/19727340

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