Mechanism of action of lenalidomide in hematological malignancies

Immunomodulatory drugs lenalidomide and pomalidomide are synthetic compounds derived by modifying the chemical structure of thalidomide to improve its potency and reduce its side effects. Lenalidomide is a 4-amino-glutamyl analogue of thalidomide that lacks the neurologic side effects of sedation an...

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Detalles Bibliográficos
Autores principales: Kotla, Venumadhav, Goel, Swati, Nischal, Sangeeta, Heuck, Christoph, Vivek, Kumar, Das, Bhaskar, Verma, Amit
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736171/
https://www.ncbi.nlm.nih.gov/pubmed/19674465
http://dx.doi.org/10.1186/1756-8722-2-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2736171/
https://www.ncbi.nlm.nih.gov/pubmed/19674465
http://dx.doi.org/10.1186/1756-8722-2-36

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